![]() ![]() MRI could also be useful to assess denervation changes of “end-organ muscles” (Table 2). Three-dimensional T1-weighted gradient echo sequences can provide a better visualization of the nerve enhancement, surrounded by CSF. The enhancement of the nerve, after gadolinium administration, is associated to disruption of the blood-nerve barrier and may be secondary to neoplasm, inflammation, demyelination, ischemia, trauma, radiation treatment, and axonal degeneration. These sequences typically show dark cranial nerves against a background of bright CSF (Fig. ![]() Several scientific articles have underlined the importance of SSFP sequences for the visualization of the cisternal spaces of cranial nerves thanks to their sub-millimetric spatial and high contrast resolution. Table 1 summarizes the most important sequences and features in their study. ![]() MRI is considered the gold standard in the study of cranial nerves. We believe that it could be a useful guide for radiologists and neuroradiologists to review the anatomy and the most important pathologies that involve cranial nerves and their differential diagnosis. The article is a complete pictorial overview of the imaging of cranial nerves, with anatomic and pathologic descriptions and great attention to illustrative depiction. Computed tomography (CT) allows, usually, an indirect view of the nerve and is useful to demonstrate the intraosseous segments of cranial nerves, the foramina through which they exit skull base and their pathologic changes. Magnetic resonance imaging (MRI) is considered the gold standard in the study of the cranial nerves. Cranial nerve dysfunctions may be the result of pathological processes of the cranial nerve itself or be related to tumors, inflammation, infectious processes, or traumatic injuries of adjacent structures. Therefore, it is necessary to know the most frequent pathologies that may involve cranial nerves and recognize their typical characteristics of imaging. The anatomy of cranial nerves is complex and its knowledge is crucial to detect pathological alterations in case of nervous disorders. The human body has 12 pairs of cranial nerves that control motor and sensory functions of the head and neck. ![]()
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